Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Biochemicals » Biochem-Apoptosis » MIM1 (4-(E)-[[(2Z)-2-cyclohexylimino)-4-m ethyl-1,3-thiazol-3(2H)-yl]imino]methyl]benzene-1, 2,3-triol)

MIM1 (4-(E)-[[(2Z)-2-cyclohexylimino)-4-m
ethyl-1,3-thiazol-3(2H)-yl]imino]methyl]benzene-1, 2,3-triol)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Catalog #167681
Solubility100mM in DMSO and 20mM in ethanol
Molecular FormulaC17H21N3O3S
Biological ActivityInhibitor of Mcl-1; selectively targets the BH3-binding pocket. Induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells. Also blocks Mcl-1-mediated suppression of tBID-induced Bax activation in vitro.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular FormulaC17H21N3O3S
Molecular Weight~347.43
FormSupplied as a solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links