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You are here:Home » Biochemicals » Biochem-Apoptosis » MIM1 (4-(E)-[[(2Z)-2-cyclohexylimino)-4-m ethyl-1,3-thiazol-3(2H)-yl]imino]methyl]benzene-1, 2,3-triol)

MIM1 (4-(E)-[[(2Z)-2-cyclohexylimino)-4-m
ethyl-1,3-thiazol-3(2H)-yl]imino]methyl]benzene-1, 2,3-triol)


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Catalog #167681
Solubility100mM in DMSO and 20mM in ethanol
Molecular FormulaC17H21N3O3S
Biological ActivityInhibitor of Mcl-1; selectively targets the BH3-binding pocket. Induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells. Also blocks Mcl-1-mediated suppression of tBID-induced Bax activation in vitro.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular FormulaC17H21N3O3S
Molecular Weight~347.43
FormSupplied as a solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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