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You are here:Home » Molecular Biology » Growth Factors-TGF » Activin A, Recombinant, Mouse, (Inhibin beta-1, FRP, FSH-releasing protein, human recombinant Activin A, hrActivin, Activin a, recombinant activin)

Activin A, Recombinant, Mouse, (Inhibin beta-1, FRP, FSH-releasing protein, human
recombinant Activin A, hrActivin, Activin a, recombinant activin)

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Specifications

Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Mouse Activin A has 100% amino acid sequence identity to human, rat, porcine, bovine and feline proteins. Recombinant mouse Activin A is a nonglycosylated homodimer, containing two 117aa chains, with a total molecular weight of 26.2kD.
Catalog #167743
SourceRecombinant corresponding to mouse Activin A expressed in E.coli.
Molecular Weight~26kD
Biological ActivityThe activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2ng/ml.
Endotoxin~1ug/ml
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~26kD
SourceE.coli
Purity~95% (HPLC, SDS-PAGE)
FormSupplied as a lyophilized powder in 0.02% TFA. Reconstitute with dH2O to 1mg/ml after centrifugation.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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