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You are here:Home » Molecular Biology » Growth Factors-TGF » Activin A, Recombinant, Rat (Inhibin beta-1, FRP, FSH-releasing protein, human recombinant Activin A, hrActivin, Activin a, recombinant activin)

Activin A, Recombinant, Rat (Inhibin beta-1, FRP, FSH-releasing protein, human recombinant
Activin A, hrActivin, Activin a, recombinant activin)

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Specifications

Activin A is a member of the TGFbeta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Rat Activin A has 100% amino acid sequence identity to human, mouse, porcine, bovine and feline proteins. Recombinant rat Activin A is a non-glycosylated homodimer, containing two 117aa chains, with a total molecular weight of 26.2kD.
Catalog #167744
SourceRecombinant corresponding to rat Activin A expressed in E.coli.
Molecular Weight~26kD
Biological ActivityThe activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2ng/ml.
Endotoxin~0.1EU/ug purified protein.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~26kD
SourceE.coli
Purity~95% (HPLC, SDS-PAGE)
FormSupplied as lyophilized powder in 0.02% TFA. Reconstitute with dH2O to 1.0mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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