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You are here:Home » Biochemicals » Biochem-Inflammation » LY-333,531 hydrochloride (Ruboxistaurin)

LY-333,531 hydrochloride (Ruboxistaurin)


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An isozyme-selective inhibitor of protein kinase Cb (PKCb). Inhibits both the PKCbI (IC =4.7 nM) and PKCbII (IC =5.9nm) isozymes. LY-333,531 is 76- and 61-fold more selective for inhibition of PKCbI and PKCbII over PKCa.
Catalog #167906
Molecular Weight~505.01
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number169939-93-9
Molecular FormulaC28H29CIN4O3
Molecular Weight~505.01
Purity~96% (NMR)
FormSupplied as a red solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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