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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -Artemis (A SCID, A SCID protein, Artemis protein, ASCID, DCLRE1C, DCLRE1C DNA cross link repair 1C, DCLRE1C protein)

Anti -Artemis (A SCID, A SCID protein, Artemis protein, ASCID, DCLRE1C, DCLRE1C DNA cross
link repair 1C, DCLRE1C protein)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.
Catalog #168034
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:10,000-1:20,000
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa482-495 from human Artemis.
SpecificityRecognizes human artemis.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesA SCID antibody, A SCID protein antibody, Artemis protein antibody, ASCID antibody, DCLRE1C antibody, DCLRE1C DNA cross link repair 1C antibody, DCLRE1C protein antibody


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