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You are here:Home » Molecular Biology » Growth Factors-BMP » BMP7, Recombinant, Human, 144aa, His-Tag (Bone Morphogenetic Protein 7, OP-1)

BMP7, Recombinant, Human, 144aa, His-Tag (Bone Morphogenetic Protein 7, OP-1)

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Specifications

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity.
Catalog #169260
SourceRecombinant protein corresponding to human BMP7, fused to His-tag expressed in Nicotiana benthamiana.
Molecular Weight~16.5, 18-20kD
Endotoxin<0.04EU/ug
Biological ActivityThe biological activity of BMP-7 is measured by its ability to induce alkaline phosphatase production by ATDC5 cells.
AA SequenceHHHHHHSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~16.5, 18-20kD
SourceNicotiana benthamiana
Purity~97% (SDS-PAGE)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 0.05M Tris HCl, pH 7.4. Reconstitute in sterile H2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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