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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL11, Recombinant, Human, aa1-97 (C-C Motif Chemokine 11, SCYA11, MGC22554)

CCL11, Recombinant, Human, aa1-97 (C-C Motif Chemokine 11, SCYA11, MGC22554)

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Specifications

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
Catalog #169289
SourceRecombinant protein corresponding to aa1-97 from human CCL11expressed in E. coli (Accession# P51671).
Molecular Weight~9kD
Endotoxin<0.1ng/ug (1EU/ug)
Biological ActivityActivity was determined by the ability to induce chemotaxis of purified eosinophils at concentrations ranging between 50-100ng/ml.
AA SequenceMKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~9kD
SourceE. coli
Purity~97% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a liquid in 100mM NaCl, 20mM Tris, pH 8.0.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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