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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL15, Recombinant, Human, aa22-113 (C-C Motif Chemokine 15, HCC-2, HMRP-2B, LKN1, Lkn-1, MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15)

CCL15, Recombinant, Human, aa22-113 (C-C Motif Chemokine 15, HCC-2, HMRP-2B, LKN1, Lkn-1,
MIP-1d, MIP-5, NCC-3, NCC3, SCYA15, SCYL3, SY15)

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Specifications

This gene, CCL15, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene is chemotactic for T cells and monocytes and induces N-acetyl-beta-D-glucosaminidase release in monocytes. It induces changes in intracellular calcium concentration in monocytes and is thought to act through the CCR1 receptor. Read-through transcripts are expressed that include exons from the downstream cytokine gene CCL14.
Catalog #169295
SourceRecombinant protein corresponding to aa22-113 from human CCL15 expressed in E. coli (Accession# Q16663).
Molecular Weight~10kD
Endotoxin<0.1ng/ug (1EU/ug)
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 2.0-40.0ng/ml.
AA SequenceQFINDAETELMMSKLPLENPVVLNSFHFAADCCTSYISQSIPCSLMKSYFETSSECSKPGVIFLTKKGRQVCAKPSGPGVQDCMKKLKPYSI
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~10kD
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 20mM PBS, 100mM NaCl, pH 7.5. Reconstitute in ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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