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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL16, Recombinant, Human, aa24-120 (C-C Motif Chemokine 16, CKb12, HCC-4, ILINCK, LCC-1, LEC, LMC, MGC117051, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4)

CCL16, Recombinant, Human, aa24-120 (C-C Motif Chemokine 16, CKb12, HCC-4, ILINCK, LCC-1,
LEC, LMC, MGC117051, Mtn-1, NCC-4, NCC4, SCYA16, SCYL4)

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Specifications

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10.
Catalog #169296
SourceRecombinant protein corresponding to aa24-120 from human CCL16 expressed in E. coli (Accession# O15467).
Molecular Weight~11kD
Endotoxin<0.1ng/ug (1EU/ug)
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 2.0-40.0ng/ml.
AA SequenceQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~11kD
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 20mM PBS, 100mM NaCl, pH 7.5. Reconstitute in ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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