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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL17, Recombinant, Human, aa24-94 (C-C Motif Chemokine 17, A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC)

CCL17, Recombinant, Human, aa24-94 (C-C Motif Chemokine 17, A-152E5.3, ABCD-2, MGC138271,
MGC138273, SCYA17, TARC)

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Specifications

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Catalog #169297
SourceRecombinant protein corresponding to aa24-94 from human CCL17 expressed in E. coli (Accession# Q92583).
Molecular Weight~8kD
Endotoxin<0.1ng/ug (1EU/ug)
Biological ActivityDetermined by its ability to chemoattract human T cells using a concentration range of 2.0-40.0ng/ml.
AA SequenceARGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~8kD
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 20mM PBS, 100mM NaCl, pH 7.5. Reconstitute in ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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