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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL2, Recombinant, Rat (C-C Motif Chemokine 2, MCP-1, Scya2)

CCL2, Recombinant, Rat (C-C Motif Chemokine 2, MCP-1, Scya2)

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Specifications

Monocyte Chemotactic Protein 1 (MCP-1), also known as CCL2, is thought to be produced by injured or infected tissues. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells.
Catalog #169304
SourceRecombinant protein corresponding to rat Ccl2 expressed in E. coli (Accession# P14844).
Molecular Weight~14.1kD
Endotoxin<0.01ng/ug or <0.1EU/ug
Biological ActivityRecombinant rat Ccl2 is fully biologically active when compared to a standard. The activity is determined by the ability of MCP-1 to chemoattract human monocytes using a concentration of 4-15ng/ml.
AA SequenceQPDAVNAPLTCCYSFTGKMIPMSRLENYKRITSSRCPKEAVVFVTKLKREICADPNKEWVQKYIRKLDQNQVRSETTVFYKIASTLRTSAPLNVNLTHKSEANASTLFSTTTSSTSVEVTSMTEN
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~14.1kD
SourceE. coli
PurityPurified.
ConcentrationAs reported
FormSupplied as a lyophilized powder. Reconstitute in sterile H2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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