Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Molecular Biology » Growth Factors-CCL » CCL21, Recombinant, Human, aa1-134 (C-C Motif Chemokine 21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4, MGC34555)

CCL21, Recombinant, Human, aa1-134 (C-C Motif Chemokine 21, 6Ckine, CKb9, ECL, SCYA21,
SLC, TCA4, MGC34555)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
Catalog #169307
SourceRecombinant protein corresponding to aa1-134 from human CCL21 expressed in E. coli (Accession# O00585).
Molecular Weight~12kD
Endotoxin<0.1ng/ug (1EU/ug)
Biological ActivityDetermined by its ability to chemoattract total lymphocyte population using a concentration range of 10.0-100.0ng/ml.
AA SequenceMAQSLALSLLILVLAFGIPRTQGSDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSKGCKRTERSQTPKGP
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~12kD
SourceE. coli
Purity~95% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 2.5% glycine, 0.5% sucrose, 0.01% Tween 80, 5mM Glutamic acid, pH 4.5. Reconstitute in ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links