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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL23, Recombinant, Human, aa22-120 (C-C Motif Chemokine 23, CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23)

CCL23, Recombinant, Human, aa22-120 (C-C Motif Chemokine 23, CK-BETA-8, CKb8, Ckb-8,
Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23)

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Specifications

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified.
Catalog #169309
SourceRecombinant protein corresponding to aa22-120 from human CCL23 expressed in E. coli (Accession# P55773).
Molecular Weight~11kD
Endotoxin<0.1ng/ug (1EU/ug)
Biological ActivityDetermined by its ability to chemoattract human T cells using a concentration range of 2.0-40.0ng/ml.
AA SequenceRVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~11kD
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 20mM PBS, 100mM NaCl, pH 7.5. Reconstitute in ddH2O. Reconstitute in ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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