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You are here:Home » Molecular Biology » Growth Factors-GM-CSF » CSF2, Recombinant, Rat (Granulocyte-macrophage Colony Stimulating Factor 2, Gm-csf, Gmcsf)

CSF2, Recombinant, Rat (Granulocyte-macrophage Colony Stimulating Factor 2, Gm-csf, Gmcsf)

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Specifications

Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is hematopoietic factor produced by entothelial cells, monocytes, fibroblasts and T cells in response to a number of inflammatory mediators. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. Human and mouse GM-CSF show no cross-reactivity.
Catalog #169357
SourceRecombinant protein corresponding to rat Csf2 expressed in E. coli (Accession# P48750).
Molecular Weight~14.6kD
Endotoxin<0.01ng/ug or <0.1EU/ug
Biological ActivityRecombinant rat Csf2 has full biological activity when compared to a standard. The ED50, as determined by the dose-dependant proliferation of the mouse FDC-P1 cell line, is <0.01ng/ml.
AA SequenceMAPTRSPNPVTRPWKHVDAIKEALSLLNDMRALENEKNEDVDIISNEFSIQRPTCVQTRLKLYKQGLRGNLTKLNGALTMIASHYQTNCPPTPETDCEIEVTTFEDFIKNLKGFLFDIPFDCWKPVQK
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~14.6kD
SourceE. coli
PurityPurified.
ConcentrationAs reported
FormSupplied as a lyophilized powder in 20mM NaHCO3. Reconstitute in sterile H2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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