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You are here:Home » Molecular Biology » Growth Factors-CXCL » CXCL12 Beta, Recombinant, Feline (C-X-C motif Chemokine 12, Stromal Cell-derived Factor 1, PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1)

CXCL12 Beta, Recombinant, Feline (C-X-C motif Chemokine 12, Stromal Cell-derived Factor 1,
PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1)

Pricing

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Specifications

For background information on chemokines, see CXCL1 (MIM 155730). Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF (see MIM 191160), or IL1 (see MIM 147760). The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
Catalog #169375
SourceRecombinant protein corresponding to cat CXCL12 expressed in E. coli (Accession# O62657-2).
Molecular Weight~8.5kD
Endotoxin<0.01ng/ug or <0.1EU/ug
Biological ActivityDetermined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2, is typically in the range of 10-75ng/ml.
AA SequenceKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~8.5kD
SourceE. coli
PurityPurified.
ConcentrationAs reported
FormSupplied as a lyophilized powder. Reconstitute in sterile H2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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