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You are here:Home » Molecular Biology » Growth Factors-BCA-1 » CXCL13, Recombinant, Human, aa22-109 (B Lymphocyte Chemoattractant, Angie, BLR-1, C-X-C Motif Chemokine 13)

CXCL13, Recombinant, Human, aa22-109 (B Lymphocyte Chemoattractant, Angie, BLR-1, C-X-C
Motif Chemokine 13)

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Specifications

B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.
Catalog #169382
SourceRecombinant protein corresponding to aa22-109 from human CXCL13 expressed in E. coli (Accession# Q53X90).
Molecular Weight~10kD
Biological ActivityDetermined by its ability to chemoattract human T cells using a concentration range of 2.0-10.0ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~10kD
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 20mM PBS, 100mM NaCl, pH 7.5. Reconstitute in ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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