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You are here:Home » Molecular Biology » Growth Factors-Defensin » DEFB1, Recombinant, Human (Beta-defensin 1, BD1, DEFB-1, DEFB101, HBD1, MGC51822)

DEFB1, Recombinant, Human (Beta-defensin 1, BD1, DEFB-1, DEFB101, HBD1, MGC51822)

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Specifications

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
Catalog #169393
SourceRecombinant protein corresponding to human DEFB1 expressed in E. coli (Accession# P60022).
Molecular Weight~5kD
Endotoxin<0.1ng/ug
Biological ActivityDetermined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1ug/ml.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~5kD
SourceE. coli
Purity~98% (SDS-PAGE)
ConcentrationAs reported
FormSupplied as a lyophilized powder in 20mM PBS, 130mM sodium chloride, pH 7.4. Reconstitute in sterile H2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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