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You are here:Home » Molecular Biology » Growth Factors-FGF » FGF1, Recombinant, Human, aa16-155 (Acidic Fibroblast Growth Factor 1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1)

FGF1, Recombinant, Human, aa16-155 (Acidic Fibroblast Growth Factor 1, AFGF, ECGF,
ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1)

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Specifications

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.
Catalog #169433
SourceRecombinant protein corresponding to aa16-155 from human FGF1 expressed in E. coli (Accession# NP_000791).
Molecular Weight~15.9kD
Biological ActivityThe ED50 for this effect is <2.9ng/ml, measured in a cell proliferation assay using NIH-3T3 cell (corresponds to >340,000units/ml).
AA SequenceMFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~15.9kD
SourceE. coli
Purity~95% (SDS-PAGE)
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris, pH 7.0, 100mM NaCl.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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