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You are here:Home » Molecular Biology » Growth Factors-FGF » FGF19, Recombinant, Human (Fibroblast Growth Factor 19)

FGF19, Recombinant, Human (Fibroblast Growth Factor 19)

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Specifications

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.
Catalog #169437
SourceRecombinant protein corresponding to human FGF19 expressed in E. coli (Accession# NP_005108.1).
Molecular Weight~21.8kD
Endotoxin<0.1ng/ug
Biological ActivityDetermined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 50-200ng/ml.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~21.8kD
SourceE. coli
Purity~95% (SDS-PAGE)
ConcentrationAs reported
FormSupplied as a lyophilized powder. Reconstitute in sterile H2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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