Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Molecular Biology » Growth Factors-GDF » GDF5, Recombinant, Human (Growth Differentiation Factor 5, BMP14, CDMP1, LAP4, SYNS2)

GDF5, Recombinant, Human (Growth Differentiation Factor 5, BMP14, CDMP1, LAP4, SYNS2)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Catalog #169477
SourceRecombinant protein corresponding to human GDF5 expressed in E. coli (Accession# P43026).
Molecular Weight~26.8kD
Endotoxin<0.01ng/ug or <0.1EU/ug
Biological ActivityThe activity is determined by the ability to induce alkaline phosphatase activity in ATDC5 cells is typically 1-2ug/ml.
AA SequenceAPSATRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~26.8kD
SourceE. coli
PurityPurified.
ConcentrationAs reported
FormSupplied as a lyophilized powder. Reconstitute in sterile H2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links