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You are here:Home » Molecular Biology » Growth Factors-GDF » GDF6, Recombinant, Human (Growth Differentiation Factor 6, BMP13, CDMP2, KFS, KFSL, MGC158100, MGC158101, SGM1)

GDF6, Recombinant, Human (Growth Differentiation Factor 6, BMP13, CDMP2, KFS, KFSL,
MGC158100, MGC158101, SGM1)

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Specifications

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.
Catalog #169478
SourceRecombinant protein corresponding to human GDF6 expressed in E. coli (Accession# Q6KF10).
Molecular Weight~27kD
Endotoxin<0.1ng/ug
Biological ActivityThe ED50 as determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is in the range of 2-3ug/ml.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~27kD
SourceE. coli
Purity~95% (SDS-PAGE)
ConcentrationAs reported
FormSupplied as a lyophilized powder. Reconstitute in sterile H2O, BSA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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