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You are here:Home » Molecular Biology » Growth Factors-G-CSF » Macrophage Colony Stimulating Factor, Recombinant, Human, aa33-181 (CSF1, MCSF, MGC31930)

Macrophage Colony Stimulating Factor, Recombinant, Human, aa33-181 (CSF1, MCSF, MGC31930)

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Specifications

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Four transcript variants encoding three different isoforms have been found for this gene.
Catalog #169505
SourceRecombinant protein corresponding to aa33-181 from human CSF1 expressed in baculovirus infected Bombyx Mori (Accession# P09603).
Molecular Weight~42kD
Endotoxin<0.1ng/ug (1EU/ug)
Biological ActivityThe ED50 was determined by the dose-dependent stimulation of the proliferation of of M-NFS-60 cells is <1.0ng/ml.
Specific Activity>1x106 units/mg
AA SequenceEEVSEYCSHMIGSGHLQSLQRLIDSQMETSCQITFEFVDQEQLKDPVCYLKKAFLLVQDIMEDTMRFRDNTPNAIAIVQLQELSLRLKSCFTKDYEEHDKACVRTFYETPLQLLEKVKNVFNETKNLLDKDWNIFSKNCNNSFAECSSQ
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~42kD
SourceBaculovirus infected Bombyx Mori
Purity~95% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder in PBS, pH 7.0. Reconstitute in ddH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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