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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -BAFF (B Cell-activating Factor)

Anti -BAFF (B Cell-activating Factor)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Binds to tnfrsf13b/taci and tnfrsf17/bcma. tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. A third b-cell specific baff-receptor (baffr/br3) promotes the survival of mature b-cells and the b-cell response. B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays. Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin.
Catalog #169520
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
HybridomaF0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No13F203
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography
ImmunogenRecombinant protein corresponding to aa134-285 from human BAFF, expressed in E. coli.
SpecificityRecognizes human BAFF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesB-cell-activating Factor


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