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You are here:Home » Molecular Biology » Growth Factors-CXCL » CXCL10, Recombinant, Human, His-Tag (C-X-C Motif Chemokine 10, 10 kDa Interferon gamma-induced Protein, Gamma-IP10, IP-10, Small-inducible Cytokine B10, INP10, SCYB10)

CXCL10, Recombinant, Human, His-Tag (C-X-C Motif Chemokine 10, 10 kDa Interferon
gamma-induced Protein, Gamma-IP10, IP-10, Small-inducible Cytokine B10, INP10, SCYB10)

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Specifications

Human Chemokine (C-X-C motif) ligand 10 (CXCL10), also known as Interferon gamma- inducible protein-10 (IP-10), is a non-ELR chemokine secreted by various cell types including monocytes, endothelial cells and fibroblasts in response to IFN-gamma. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemo- attraction for activated T-lymphocytes, inhibition of angiogenesis and antitumor activity.
Catalog #169661
SourceRecombinant protein corresponding to aa22-98 from human CXCL10 at C-terminus, fused to His-tag, expressed in E.coli.
Molecular Weight~8.8kD
Endotoxin<0.1ng/ug (1IEU/ug)
Biological ActivityThe ED50 of rHu CXCL10 as determined by its ability to chemoattract human CXCR3 transfected BaF3 mouse proB cells was 0.02-0.06 ug/ml.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~8.8kD
SourceE. coli
Purity~95% (SDS-PAGE, HPLC)
Concentration~0.1mg/ml after reconstitution
FormSupplied as a lyophilized powder in 20mM PBS, pH 7.0, 150mM sodium chloride. Reconstitute with sterile dH2O PBS to 0.1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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