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You are here:Home » Growth Factors, Cytokines » Growth Factors-CXCL » CXCL14, Recombinant, Human (C-X-C Motif Chemokine 14, Chemokine BRAK, MIP-2G, Small-inducible Cytokine B14, MIP2G, NJAC, SCYB14, PSEC0212, UNQ240/PRO273)

CXCL14, Recombinant, Human (C-X-C Motif Chemokine 14, Chemokine BRAK, MIP-2G,
Small-inducible Cytokine B14, MIP2G, NJAC, SCYB14, PSEC0212, UNQ240/PRO273)

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Specifications

Human Chemokine (C-X-C motif) ligand 14 (hCXCL14), also known as breast and kidney- expressed chemokine (BRAK), MIP-2 gamma, kidney-expressed chemokine (KEC), and B cell and monocyte-activating chemokine (BMAC), is a CXC chemokine constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemo-attractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 residues.
Catalog #169663
SourceRecombinant protein corresponding to 77aa of human CXCL14, expressed in E.coli.
Molecular Weight~9.4kD
Endotoxin<0.1ng/ug (1IEU/ug)
Biological ActivityThe ED50 as determined by its ability to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells was 1-10ng/ml.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~9.4kD
SourceE. coli
Purity~95% (SDS-PAGE, HPLC)
Concentration~0.1mg/ml after reconstitution
FormSupplied as a lyophilized powder from 20mM Tris HCl, 1M sodium chloride, pH 8.5. Reconstitute with sterile 18MO-cm H2O to 0.1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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