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You are here:Home » Growth Factors, Cytokines » Growth Factors-Exodus » Exodus-2, Recombinant, Mouse (Ccl21a, C-C Motif Chemokine 21a, 6Ckine, Beta-chemokine Exodus-2, Small-inducible Cytokine A21a, Thymus-derived Chemotactic Agent 4, TCA4, Scya21, Scya21a)

Exodus-2, Recombinant, Mouse (Ccl21a, C-C Motif Chemokine 21a, 6Ckine, Beta-chemokine
Exodus-2, Small-inducible Cytokine A21a, Thymus-derived Chemotactic Agent 4, TCA4, Scya21,
Scya21a)

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Specifications

Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% aa homology. Recombinant mouse Exodus-2 is a nonglycosylated protein, containing 110aa, with a molecular weight of 12kD.
Catalog #169679
SourceRecombinant protein corresponding to 10aa from mouse Exodus-2, expressed in E. coli.
Molecular Weight~12kD
Biological ActivityDetermined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200ng/ml- 600ng/ml.
Amino Acid SequenceSDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
Endotoxin<0.1ng/ug
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~12kD
SourceE. coli
Purity~98% (SDS-PAGE)
Concentration~0.1mg/ml after reconstitution
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O to 0.1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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