Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Receptors, Estrogen » Anti -ER (Estrogen Receptor)

Anti -ER (Estrogen Receptor)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Rabbit Affinity Purified IH
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Catalog #169864
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:100-1:200
Optimal dilutions to be determined by the researcher.
Positive controlHuman breast tumor tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at 4°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone NoS21-V
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 20mM Tris-HCl, 20mg/ml BSA, pH 8.0.
PurityPurified by immunoaffinity chromatography.
ImmunogenPeptide derived from C-terminal sequence of human estrogen receptor alpha. Cellular localization: nuclear membrane, cytoplasm
SpecificityRecognizes human estrogen reeptor alpha.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links