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You are here:Home » Molecular Biology » Growth Factors-CXCL » CXCL10, Recombinant, Human (C-X-C motif chemokine 10 (10kD interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) Cleaved into: CXCL10(1-73))

CXCL10, Recombinant, Human (C-X-C motif chemokine 10 (10kD interferon gamma-induced
protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) Cleaved into: CXCL10(1-73))

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Specifications

Human Chemokine (C-X-C motif) ligand 10(CXCL10),also known as Interferon gamma-inducible protein-10 (IP-10), is a non-ELR chemokine secreted by various cell types including monocytes, endothelial cells and fibroblasts in response to IFN-y. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemo-attraction for activated T-lymphocytes, inhibition of angiogenesis and antitumor activity.
Catalog #169944
SourceRecombinant protein corresponding to human CXCL10, expressed in E. coli.
Molecular Weight~8.8kD
Biological ActivityThe ED50 of rHu CXCL10 as determined by its ability to chemoattract human CXCR3 transfected BaF3 mouse proB cells was 0.02-0.06ug/ml.
Endotoxin<0.1ng/ug (1IEU/ug)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~8.8kD
SourceE. coli
Purity~95% (SDS-PAGE, HPLC)
Concentration~1mg/ml after reconstitution
FormSupplied as a lyophilized powder in 20mM PB, pH 7.0, 150mM NaCl. Reconstitute with 1x PBS.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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