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You are here:Home » Antibodies » Abs to Serotonin Receptors » Anti -5-HT6 (HTR6, 5-HT6R, 5-HT-6, 5- hydroxytryptamine Receptor 6, 5-HT6 Receptor, 5-HT6 Serotonin Receptor, 5-hydroxytryptamine 6 Receptor, Serotonin 6 Receptor, Serotonin Receptor 6, Serotonin 5-HT-6 Receptor, Serotonin Type 6 Receptor)

Anti -5-HT6 (HTR6, 5-HT6R, 5-HT-6, 5- hydroxytryptamine Receptor 6, 5-HT6 Receptor, 5-HT6
Serotonin Receptor, 5-hydroxytryptamine 6 Receptor, Serotonin 6 Receptor, Serotonin
Receptor 6, Serotonin 5-HT-6 Receptor, Serotonin Type 6 Receptor)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission. This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders. The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion. Some antidepressants and antipsychotics are potent 5-HT6 Receptor antagonists, making this gene valuable for the pharmaceutical industry. 5-HT6 may be involved in the pathogenesis of mood disorders, schizophrenia, in Alzheimer's disease. A splice variant that has a 289bp deletion in the transmembrane region IV and the third intracellular loop has been isolated.
Catalog #170104
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 17aa from the C-terminus of human 5-HT6. Species sequence homology: monkey and equine.
SpecificityRecognizes human 5-HT6. Species Crossreactivity: chimpanzee and gorilla.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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