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You are here:Home » Antibodies » Abs to Serotonin Receptors » Anti -HTR2B (5-hydroxytryptamine Receptor 2B, 5-HT-2B, 5-HT2B, 5-HT(2B), Serotonin Receptor 2B)

Anti -HTR2B (5-hydroxytryptamine Receptor 2B, 5-HT-2B, 5-HT2B, 5-HT(2B), Serotonin
Receptor 2B)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
5-HT2B, a Serotonin Receptor, activates phospholipase C upon binding serotonin, which results in a rise in intracellular calcium. It is known that 5-HT2B regulates cardiovascular function during development and in adulthood; mice lacking functional 5-HT2B receptors died of heart defects during gestation or neonatally, and adult mutant mice displayed cardiopathy, including myocyte disarray and ventricular dilation.
Catalog #170861
ApplicationsSuitable for use in Immunohistochemistry. Not suitable for Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 4-6ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 15aa from 2nd extracellular domain of human 5HT2B Receptor. Species sequence homology: bat and bovine (90%).
SpecificityRecognizes human 5HT2B. Species crossreactivity: chimpanzee, gorilla, orangutan, gibbon and monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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