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You are here:Home » Antibodies » Abs to Tetraspanin » Anti -TM4SF6 (A15 Homolog, Tetraspanin TM4-D, Tetraspanin-6, Tetraspanin 6, T245, T245 Protein, Tetraspan TM4SF, TSPAN6, TSPAN-6)

Anti -TM4SF6 (A15 Homolog, Tetraspanin TM4-D, Tetraspanin-6, Tetraspanin 6, T245, T245
Protein, Tetraspan TM4SF, TSPAN6, TSPAN-6)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013].
Catalog #171347
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 18aa from the internal region of human TM4SF6/TSPAN6. Species sequence homology: gibbon, bovine and equine.
SpecificityRecognizes human TM4SF6/TSPAN6. Species Crossreactivity: chimpanzee, gorilla and orangutan.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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