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You are here:Home » Antibodies » Abs to Urotensin » Anti -Urotensin II

Anti -Urotensin II

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E
Urotensins are neuropeptide secreted from the urophysis in the caudal neurosecretory system of the fishes. Two bioactive Urotensins, U1 and UII have been cloned from various species including mammals. UI is 41aa peptide, which showed prolonged hypotensive effects in mammals. It is structurally similar to mammalian corticotropin-releasing factor. UII is a vasoactive 'somatostatin-like" 12-aa cyclic peptide with similarity to somatostatin-14. Human UII is composed of only 11aa residues, while fish and frog UII possess 12 and 13aa, respectively. The cyclic region of the UII, which is responsible for the biological activity of the peptide, has been fully conserved from fish to human. UII expression has been observed predominantly in the spinal cord.
Catalog #171799
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with 20ul ddH2O.
PurityPurified
ImmunogenSynthetic peptide corresponding to human Urotensin II.
SpecificityRecognizes human Urotensin II. Species Crossreactivity: human Endothelin (1-21), human Big Endothelin (1-38), human Urodilatin human ANP (1-28) human BNP (-32) Adrenomedulin (1-52) Relaxin Somatostatin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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