Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein.
Applications
Suitable for use in Peptide ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Peptide ELISA: 1:32,000 Western Blot: 0.02-0.1ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-KQERESAKSELTES, from the C-terminus of the protein sequence according to NP_005091.2; NP_653080.1.
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human AKAP12. This antibody is expected to recognize both reported isoforms.
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