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208105 Goat Anti-CYP2C8 (CPC8, CYPIIC8, Cytochrome P450 2C8, Cytochrome P450 form 1, Cytochrome P450 IIC2, Cytochrome P450 MP-12, Cytochrome P450 MP-20, Cytochrome P450, family 2, subfamily C, polypeptide 8, Cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), Polypeptide 8, Flavoprotein-linked monooxygenase, Microsomal monooxygenase, MP-12/MP-20, P450 form 1, S-mephenytoin 4-hydroxylase, Xenobiotic monooxygenase)

Specifications
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_000761.3; NP_001185782.1; NP_001185783.1
Gene ID
1558
Gene #
CYP2C8
Shipping Temp
Blue Ice
Storage Temp
-20°C

Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity.

Applications
Suitable for use in Peptide ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Peptide ELISA: 1:32,000 Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-KNVALTRSYIREK, from the internal region of the protein sequence according to NP_000761.3; NP_001185782.1; NP_001185783.1.
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human CYP2C8. This antibody is expected to recognize all reported isoforms (NP_000761.3; NP_001185782.1; NP_001185783.1). No cross-reactivity with other 2C proteins expected. Reported variants represent identical protein: NP_001185782.1, NP_001185784.1.
Conjugates
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