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209418 Rabbit Anti-ADRM1 (Adhesion-regulating Molecule 1, ARM1, ARM-1, GP110)

Specifications
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q16186
Isotype
IgG
Grade
Affinity Purified
Applications
IF IHC IP WB
Crossreactivity
Hu Mo Rt
Gene ID
11047
Gene #
ADRM1
Shipping Temp
Blue Ice
Storage Temp
-20°C

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.

Applications
Suitable for use in Immunoprecipitation, Immunofluorescence, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended Dilution
Western Blot: 1:500-1:2000 Immunoprecipitation: 1:20-1:50 Immunohistochemistry: 1:50-1:200 Immunofluorescence: 1:50-1:200 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant protein corresponding to human ADRM1.
Form
Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Purity
Purified by affinity chromatography.
Specificity
Recognizes ADRM1. Species Crossreactivity: human, mouse, rat
Conjugates
Pricing
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