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218894 Rabbit Anti-CRHBP (Corticotropin-releasing Hormone-binding Protein, CRFBP, CRF-BP)

Specifications
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P24387
Isotype
IgG
Grade
Affinity Purified
Applications
IF IHC WB
Crossreactivity
Hu
Gene ID
1393
Shipping Temp
Blue Ice
Storage Temp
-20°C

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.

Applications
Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended Dilution
Immunofluorescence: 1:50-1:100 Western Blot: 1:500-1:2000 Immunohistochemistry: 1:50-1:200 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Recombinant protein corresponding to human CRHBP.
Form
Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Purity
Purified by affinity chromatography.
Specificity
Recognizes human CRHBP.
Conjugates
Pricing
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