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You are here:Home » Antibodies » Antibodies-Transcription Factors, Zinc (Ring) Finger » Anti -A20 Zinc Finger Protein

Anti -A20 Zinc Finger Protein


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Clone Host Grade Applications
Monoclonal Mouse B
Catalog #A0000-20
Western Blot (1:1'000)
A20 is a zinc finger protein that renders cells resistant to apoptosis. A20-deficient mice develop severe inflammation and are hyper-responsive to LPS. S.M. O'Reilly & P.N. Moynagh have shown that full length A20 inhibits activation of NF-kB and AP-1 by TLR4 [1]. A20 associates with A20-binding inhibitor of NF-kB (ABIN)-1 and -2 [2-4], which interfere with NF-kB activation upstream of the IKK complex.
Clone TypeMonoclonal
Clone No6D88
FormSupplied as a liquid in PBS containing 0.02% sodium azide.
ImmunogenZinc finger domain corresponding to aa 375-537 of human A20.
SpecificityRecognizes human A20.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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