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17-AAG (17-allylamino-17-demethoxygeldanamycin, Telatinib, Tanespimycin, NSC-330507, CNF-101, KOS-953, GLD-36, CP 127374)
17-AAG (17-allylamino-17-demethoxygeldanamycin, Telatinib, Tanespimycin, NSC-330507, CNF-101, KOS-953, GLD-36, CP 127374)
Pricing
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| Semi-synthetic derivative of geldanamycin, demonstrating greater stability and lower in vivo toxicity than its parent compound. 17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. | | | Catalog # | A0001-85 | | Solubility | Soluble in DMSO at 150mg/ml; soluble in ethanol at 5mg/ml; very poorly soluble in water; maximum solubility in plain water is estimated to be about 20-50uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. | | Storage and Stability | May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. | | CAS Number | 75747-14-7 | | Molecular Formula | C31H43N3O8 | | Molecular Weight | 585.69 | | Purity | ~99% | | Form | Supplied as a purple powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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