You are here:Home
»
Antibodies
»
Abs to Transport Proteins
»
Anti -ABC A1 (ATP-binding Cassette (ABC) Tansporter 1)
Anti -ABC A1 (ATP-binding Cassette (ABC) Tansporter 1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
E B IP IH |
|
| Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of | | | plasma HDL, cholesterol ester depositing in the reticulo- endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, | | | and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. | | | Catalog # | A0004-01 | | Applications | Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 7i4 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide. | | Purity | Purified. | | Immunogen | Synthetic peptide from human ABC A1 containing amino acids 1800-2260. | | Specificity | Recognizes human ABCA1. Species Crossreactivity: mouse and chicken. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
