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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -ABC A1 (ATP-binding Cassette (ABC) Tansporter 1)

Anti -ABC A1 (ATP-binding Cassette (ABC) Tansporter 1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IP IH
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of
plasma HDL, cholesterol ester depositing in the reticulo- endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex,
and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Catalog #A0004-01
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No7i4
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified.
ImmunogenSynthetic peptide from human ABC A1 containing amino acids 1800-2260.
SpecificityRecognizes human ABCA1. Species Crossreactivity: mouse and chicken.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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