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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -ABCA1 (ABC 1, ABC Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, HDLDT1, TGD)

Anti -ABCA1 (ABC 1, ABC Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette
Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, HDLDT1, TGD)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified B FC IF
The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABCA subfamily, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease. Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency.
Catalog #A0004-01A
ApplicationsSuitable for use in Flow Cytometry, Immunofluorescence, and Western Blot. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:10-1:200; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B15
HostRat
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenABCA1 transfected HeLa cells.
SpecificityRecognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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