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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -ABCB8 (Mitochondrial ATP-binding Cassette 1, M-ABC1, ATP-binding Cassette Sub-family B Member 8, Mitochondrial, MABC1)

Anti -ABCB8 (Mitochondrial ATP-binding Cassette 1, M-ABC1, ATP-binding Cassette Sub-family
B Member 8, Mitochondrial, MABC1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. The protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Catalog #A0004-01Q
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KKPEGPRSHQHK, from ABCB8, at
C-terminal (NP_009119.2).
SpecificityRecognizes ABCB8. Species sequence homology: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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