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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -ABCA1 (ATP-binding Cassette Sub-family A Member 1, ATP-binding Cassette Transporter 1, ABC-1, ATP-binding Cassette 1, Cholesterol Efflux Regulatory Protein, ABC1, CERP)

Anti -ABCA1 (ATP-binding Cassette Sub-family A Member 1, ATP-binding Cassette Transporter
1, ABC-1, ATP-binding Cassette 1, Cholesterol Efflux Regulatory Protein, ABC1, CERP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IP IH
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Catalog #A0004-02J
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 3-6ug/ml
Western Blot: 1:1,000-1:2,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10K91
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified.
ImmunogenSynthetic peptide corresponding to aa1800-2260.
SpecificityRecognizes ABCA1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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