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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -ABCA2 (ATP-binding Cassette Sub-family A Member 2, ATP-binding Cassette Transporter 2, ATP-binding Cassette 2, ABC2, KIAA1062)

Anti -ABCA2 (ATP-binding Cassette Sub-family A Member 2, ATP-binding Cassette Transporter
2, ATP-binding Cassette 2, ABC2, KIAA1062)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
ATP binding cassette (ABC) transporters are a large family of conserved proteins that translocate molecules across cellular membranes. ABCA2 is a 250kD member of the ABCA subfamily, which is predominantly expressed in the central nervous system, ovary and macrophages. The ABCA2 molecule shares homology with ABCA1 and ABCA7 and plays an important role in lipid metabolism. ABCA2 has been associated with Alzheimer's disease, and studies suggest that ABCA2 could also be involved in drug transport and resistance of tumours to chemotherapy.
Catalog #A0004-02N1
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KKQSDNLEQQETEP, from ABCA2, at the internal region of the protein (NP_001597.2, NP_997698.1).
SpecificityRecognizes ABCA2. Species sequence homology: Human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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