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You are here:Home » Antibodies » Abs to Disease Markers » Anti -ABCA2 (ATP Binding Cassette 2) (PE)

Anti -ABCA2 (ATP Binding Cassette 2) (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
ATP binding cassette (ABC) transporters are a large family of conserved proteins that translocate molecules across cellular membranes. ABCA2 is a 250kD member of the ABCA subfamily, which is predominantly expressed in the central nervous system, ovary and macrophages. The ABCA2 molecule shares homology with ABCA1 and ABCA7 and plays an important role in lipid metabolism. ABCA2 has been associated with Alzheimer's disease, and studies suggest that ABCA2 could also be involved in drug transport and resistance of tumors to chemotherapy.
Catalog #A0004-02S
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: Neat 10ul labels 1x10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.
Recommended Negative Controls RAT IgG2a Negative ControlRPE
RAT IgG2a Negative Control:RPE
Storage and StabilityLyophilized powder may be stored at 4°C before opening. DO NOT FREEZE! Reconstitute with ddH2O. Aliquot and store at 4ºC. Stable at 4°C as an undiluted liquid for 6 months. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9F86
HostRat
SourceMouse
Concentration~100 tests/ml
FormSupplied as a lyophilized powder in PBS, pH 7.2, 1% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenABCA2 transfected HeLa cells.
SpecificityRecognizes murine adenosine triphosphate (ATP) binding cassette transporter 2 (ABCA2).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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