Anti -ABCE1 (ATP-binding Cassette Sub-family E Member 1, 2'-5'-oligoadenylate-binding
Protein, HuHP68, RNase L Inhibitor, Ribonuclease 4 Inhibitor, RNS4I, RLI, RNASEL1,
RNASELI, RNS4I, OK/SW-cl.40)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E |
|
| Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. | | | Catalog # | A0004-03E | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:32,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to NHDKCKPKKCRQEC, from ABCE1, at N-terminal (NP_002931.2, NP_001035809.1). | | Specificity | Recognizes ABCE1. Species sequence homology: Bovine, human, mouse, canine and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -ABCE1 (ATP-binding Cassette Sub-family E Member 1, 2'-5'-oligoadenylate-binding Protein, HuHP68, RNase L Inhibitor, Ribonuclease 4 Inhibitor, RNS4I, RLI, RNASEL1, RNASELI, RNS4I, OK/SW-cl.40) |
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