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You are here:Home » Antibodies » Antibodies-Multi Drug Resistance (MDR) » Anti -ABCG1 (ATP-Binding Cassette (ABC) Sub-family G Member 1, AbC8, ATP-Binding Cassette Tansporter 8, White Protein Homolog, WHT1)

Anti -ABCG1 (ATP-Binding Cassette (ABC) Sub-family G Member 1, AbC8, ATP-Binding Cassette
Tansporter 8, White Protein Homolog, WHT1)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1.
Catalog #A0004-12B
ApplicationsSuitable for use in Western Blo and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: Theoretical molecular weight of ABCG1 is ~75.6kD,
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormAs reported
PurityPurified by peptide immunoaffinity chromatography.
ImmunogenA synthetic peptide made to an internal region of human ABCG1 (between residues 300-400).
SpecificityThe specificity of this antibody is for ABCG1. Species Crossreactivity: This antibody reacts with mouse and human protein. Other species have not been tested. There is 100%/100% identity/homology of the immunogen used for this production and the human protein sequence. There is 84%/89% for mouse and 78%/88% for rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesABC8, ABCG1, MGC34313, WHITE, WHITE1, WHT1

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