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You are here:Home » Antibodies » Abs to Spectrin » Anti -Abi-2 (ABI2, SSH3BP2, argBPIB, Abl interactor 2)

Anti -Abi-2 (ABI2, SSH3BP2, argBPIB, Abl interactor 2)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH IC
Abl-interactor (Abi) proteins are targets of Abl-family nonreceptor tyrosine kinases and are required for Rac-dependent cytoskeletal reorganization in response to growth factor stimulation (1). Abi-2 acts in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. This protein is involved in cytoskeletal reorganization, and it regulates ABL1/c-Abl-mediated phosphorylation of MENA (2).
Catalog #A0007-34M
ApplicationsSuitable for use in Western Blot, Immunocytochemistry and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000-1:10,000
Immunohistochemistry: 1:100-1:250
Immunocytochemistry: 1:100-1:250
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR7069
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSaynthetic peptide corresponding to residues in human Abi-2.
SpecificityRecognizes human Abi-2. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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