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You are here:Home » Molecular Biology » MB-Enzymes, Acetyltransferase » AcCoA Acetyltransferase 2 (ACAT2, Acetyl Coenzyme A Acetyltransferase 2, Acetoacetyl Coenzyme A Thiolase) Recombinant, Human

AcCoA Acetyltransferase 2 (ACAT2, Acetyl Coenzyme A Acetyltransferase 2, Acetoacetyl
Coenzyme A Thiolase) Recombinant, Human

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Specifications

Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3 prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
Catalog #A0220-01A
DescriptionRecombinant Human ACAT-2 produced in E.Coli is a non-glycosylated, polypeptide chain containing amino acids 1-397 and having a total molecular mass of 41.3kD. Recombinant ACAT2 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.
Applications ELISA MS Inhibition Assays Western Blotting
Storage and StabilityStore at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight41.3kD
SourceE. coli
Purity95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Concentration~0.1mg/ml
FormSupplied as a liquid in 10mM Tris, pH 8.0, 0.1M sodium chloride, 1mM DTT and 20% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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