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You are here:Home » Antibodies » Abs to Enzymes » Anti -ACACB (Acetyl-CoA Carboxylase 2, ACC-beta, ACC2, ACCB)

Anti -ACACB (Acetyl-CoA Carboxylase 2, ACC-beta, ACC2, ACCB)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.
Catalog #A0224-03C
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QLGEPDLSDKDRKD, from ACACB, at the internal region of the protein (NP_001084.2).
SpecificityRecognizes ACACB. Species sequence homology: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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