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You are here:Home » Antibodies » Abs to Enzymes, Acetylcholinesterase » Anti -Acetylcholinesterase YT blood group (Acetylcholine acetylhydrolase, ACHE, precursor, ARACHE, N-ACHE-YT)

Anti -Acetylcholinesterase YT blood group (Acetylcholine acetylhydrolase, ACHE, precursor,
ARACHE, N-ACHE-YT)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E
Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft.
Catalog #A0526-42A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q7
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 0.02M PBS, 0.25M sodium chloride, pH 7.2, with 0.1% sodium azide
PurityAscites
ImmunogenAcetylcholinesterase AChE from lysed human erythrocyte.
SpecificityAcetylcholinesterase from human and monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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